RNOtherCancer nursing2018

Caregiver Sleep and Patient Neutrophil Engraftment in Allogeneic Hematopoietic Stem Cell Transplant: A Secondary Analysis.

Timothy S Sannes, Susan K Mikulich-Gilbertson, Crystal L Natvig and 3 others

PMID 27922914

WHAT IT FOUND

Poorer caregiver sleep before transplant was associated with longer patient time to neutrophil engraftment after allogeneic hematopoietic stem cell transplant.

Worse objective and self-reported caregiver sleep related to longer engraftment; caregiver distress did not.

Key findings

01Lower caregiver sleep efficiency and greater wake after sleep onset were significantly related to longer patient time to neutrophil engraftment.

02Worse caregiver self-reported sleep quality was significantly related to longer patient time to neutrophil engraftment.

03Caregiver composite distress was not significantly related to patient time to neutrophil engraftment.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

This was a secondary exploratory analysis, not a randomised test of improving caregiver sleep, so it cannot show that caregiver sleep caused shorter engraftment. Patient sleep and many patient medical variables were not collected, so patient factors could explain the relationship. Caregiver sleep was assessed for only three days, not the longer period recommended in the paper. The analysis used baseline data from a caregiver intervention trial, and the final sample was 124 dyads after exclusions. Caregivers and patients were primarily Caucasian, which limits how broadly the result applies.

Declared interests

The authors reported no funding or conflicts of interest.

The easy way to misread this

Do not conclude that treating caregiver sleep will reduce patient time to neutrophil engraftment. This was a secondary analysis of associations in 124 dyads, not a randomised test of a sleep intervention, and patient sleep was not measured.

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