Caffeine and Insomnia in People Living With HIV From the Miami Adult Studies on HIV (MASH) Cohort.
Venkataraghavan Ramamoorthy, Adriana Campa, Muni Rubens and 8 others
PMID 28830705WHAT IT FOUND
Higher caffeine intake was associated with more insomnia symptoms in 130 adults living with HIV taking ART.
Insomnia was also associated with lower CD4 counts and higher HIV viral load. Ask about caffeine and sleep.
Key findings
01Caffeine consumption was significantly associated with higher insomnia distress, poorer sleep-related quality of life, and higher global insomnia scores after adjustment for covariates.
02Higher global insomnia scores were significantly associated with lower CD4+ T cell counts and higher HIV viral loads after adjustment for covariates.
03Participants reported mean total caffeine consumption of 337.63 ± 304.97 mg/day, with coffee and caffeinated soft drinks as the largest sources.
STILL TO COME
How it was doneWhat they foundWhat it means for RNs
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What it does not show
The 130 participants were a convenience sample from one Miami cohort, and most were African American adults with incomes below poverty, so the results may not apply to other people living with HIV. The analysis was cross-sectional, so it cannot show that caffeine caused insomnia or that insomnia worsened HIV markers. Caffeine was measured for the past 24 hours, but insomnia was measured for the past 7 days, so the exposure and outcome did not cover the same time period. Caffeine intake and insomnia were self-reported, so memory and recall bias could affect the results. There were very few participants who did not consume caffeine, and the study did not have an adequate non-caffeine comparison group.
Declared interests
The authors reported no real or perceived vested interests that could be construed as a conflict of interest.
The easy way to misread this
Do not conclude that reducing caffeine will improve sleep or HIV markers. The study only measured associations at one time point, and caffeine was reported for the past 24 hours while insomnia was reported for the past 7 days.