RNCohortEuropean journal of oncology nursing : the official journal of European Oncology Nursing Society2025

Biobehavioral correlates of multidimensional fatigue in men with prostate cancer: A secondary data analysis.

Kristin Dickinson, Kevin Kupzyk, Christopher Wichman and 4 others

PMID 40849968

WHAT IT FOUND

In men with prostate cancer receiving radiation, general, physical, and mental fatigue worsened during treatment, while emotional fatigue improved.

After treatment, general, physical, and mental fatigue improved, but emotional fatigue stayed steady.

Key findings

01During treatment, general, physical, and mental fatigue worsened, while emotional fatigue improved.

02After treatment completion, general, physical, and mental fatigue improved, while emotional fatigue remained steady.

03Anxiety and depression were positively correlated with each fatigue dimension during treatment and after treatment.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

This was a secondary analysis of a small sample, so the analysis was descriptive and exploratory. The sample was homogeneous and mostly White, so the results may not apply to other groups. Many variables were examined, so some correlations may be chance findings. Pain and difficulty sleeping were measured with brief items, which may have missed stronger relationships. The anxiety and depression measures had only marginal reliability in this sample. The fatigue questionnaire showed a floor effect and little score variation, and its clinically important difference was reported only in women with breast cancer.

Declared interests

The authors declared no conflicts of interest.

The easy way to misread this

Do not treat these correlations as evidence that any treatment reduces fatigue. The study was exploratory, used a small sample, and tested many variables, so some associations may be chance.

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