Narrative ReviewMolecular autism2020

Autism spectrum disorder at the crossroad between genes and environment: contributions, convergences, and interactions in ASD developmental pathophysiology.

Cristina Cheroni, Nicolò Caporale, Giuseppe Testa

PMID 32912338

WHAT IT FOUND

No original patient outcomes or intervention results are reported, so there is nothing here to change therapy practice.

What this paper is

This is a narrative review of autism spectrum disorder pathophysiology, covering genetic risk, environmental exposures, gene-environment interactions, and laboratory models. It summarizes published studies and ideas, but it reports no original participants, methods, or outcomes, so there is no finding here that therapists can act on.

The easy way to misread this

Do not read this review as evidence that a therapy works or that a specific exposure caused autism in an individual patient.

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The study

Certainty of evidence
Low

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    Cite

    Cristina Cheroni, Nicolò Caporale, Giuseppe Testa Autism spectrum disorder at the crossroad between genes and environment: contributions, convergences, and interactions in ASD developmental pathophysiology. Molecular autism. 2020.

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