Association of frailty with activity levels and sedentary behaviours in patients with hepatitis B cirrhosis: A cross-sectional study.
Lili Li, Xia Fu, Na He and 3 others
PMID 38268270WHAT IT FOUND
In 503 hospitalized patients with hepatitis B cirrhosis, 21.3% were frail.
Frailty was significantly associated with higher age and worse liver function, and patients who were insufficiently active and highly sedentary had 2.829 times the odds of frailty.
Key findings
0121.3% of the 503 inpatients with hepatitis B cirrhosis were classified as frail.
02Patients with insufficient physical activity (<150 min/week) and excessive sedentary behaviour (≥420 min/day) had 2.829 times higher odds of frailty compared to those with sufficient activity and no excessive sedentary behaviour.
03Age and Child-Pugh score were significantly associated with the risk of frailty in multivariable analysis.
STILL TO COME
How it was doneWhat they foundWhat it means for PTsWhat it means for OTsWhat it means for RNs
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What it does not show
The cross-sectional design prevents determining cause-and-effect relationships between activity levels, sedentary behaviour, and frailty. The study was conducted at a single site in China, limiting generalizability to other populations. The Liver Frailty Index was developed in the US and may require validation or adjustment for use in Chinese populations, although prevalence rates in this study were similar to another Chinese study. Self-reported physical activity and sedentary behaviour via questionnaire may be subject to recall or social desirability bias.
Declared interests
The authors declared no conflicts of interest.
The easy way to misread this
Do not interpret the association between sedentary behaviour and frailty as proof that reducing sitting time will reverse frailty. The cross-sectional design shows a link, not that changing behaviour causes the outcome.