PTCohortGait & posture2025

Assessment of hip joint mechanics during walking in people with Marfan syndrome.

Mariana V Jacobs, Justin M Pol, Aaron D Fain and 5 others

PMID 40334610

WHAT IT FOUND

People with Marfan syndrome reported worse hip pain and walked with different hip, pelvis and leg mechanics than controls.

Higher hip rotation loading was linked to worse hip pain, but the study did not show cause.

Key findings

01During walking, people with Marfan syndrome showed different trunk, pelvic and lower extremity mechanics than healthy controls.

02The Marfan syndrome group reported worse hip pain, symptoms, daily activity function and quality of life than controls.

03Within the Marfan syndrome group, higher hip internal rotation loading during walking was linked to worse hip pain.

STILL TO COME

How it was doneWhat they foundWhat it means for PTs

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What it does not show

The study compared groups at one time, so it cannot show whether the walking differences caused hip pain or developed because of it. Most participants with Marfan syndrome were female, so the results may not represent men with the condition. The Marfan group was older than the control group, although the analysis adjusted for age. The study looked only at level walking, so it may miss mechanics during more demanding tasks. The controls were healthy people from a local laboratory database, not a broad community sample. No intervention was tested, so the paper does not show that changing gait improves outcomes.

Declared interests

The article is tagged as NIH extramural research support, and the authors declared no conflicts of interest.

The easy way to misread this

Do not read these walking differences as proof that hip pain is caused by altered mechanics. The study measured people once and did not test whether changing gait changes pain.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →