OtherJournal of autism and developmental disorders2017

Assessment of Caregiver Inventory for Rett Syndrome.

Jane B Lane, Amber R Salter, Nancy E Jones and 7 others

PMID 28132121

WHAT IT FOUND

Caregiver burden questionnaire for Rett syndrome families had average scores below 50% of maximum, stayed similar over three months in those who completed follow-up, and linked more to parent health than child severity.

Use it to understand family strain, not to judge child impairment.

Key findings

01Caregivers' average RTT CIA score was 61.9, less than 50% of the maximum score of 130.

02Higher caregiver burden was linked to parents' worse general health and worse health than a year ago, while child clinical severity was not associated.

03The questionnaire's scores changed little over three months, and the items grouped into physical, emotional, social, and time-dependence burden.

STILL TO COME

How it was doneWhat they found

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What it does not show

The study group was mostly white and non-Hispanic, and the follow-up group was entirely white, so the results may not apply to families from other racial or ethnic backgrounds. Only 70 of 198 caregivers completed the 3-month follow-up, and those who did were slightly older and had children diagnosed at older ages. The main analysis was cross-sectional, so the study cannot show how caregiver burden changes over years or predict future burden. The burden score was more closely linked to the parent's own health than to the child's condition, and it showed no association with the child's clinical severity. The study did not have an existing Rett syndrome caregiver burden measure to compare against, so some validity checks were limited. The questionnaire was designed for Rett syndrome caregivers and may not be appropriate for families of children with other disabilities.

The easy way to misread this

Do not use the RTT CIA to judge how severe a child's Rett syndrome is, to measure therapy outcomes, or to compare families of children with other disabilities. It measures caregiver burden, showed no association with child clinical severity, and was designed only for RTT caregivers.

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The study

Participants
198 caregivers at initial visit; 70 completed follow-up; 177 with complete data for factor analysis
Certainty of evidence
Low

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    Jane B Lane, Amber R Salter, Nancy E Jones, et al. Assessment of Caregiver Inventory for Rett Syndrome. Journal of autism and developmental disorders. 2017.

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