Applying machine learning to construct an association model for lung cancer and environmental hormone high-risk factors and nursing assessment reconstruction.
Pin-Chieh Lee, Mong-Wei Lin, Hsien-Chi Liao and 2 others
PMID 38837653WHAT IT FOUND
A database model reported abnormal blood and urine cadmium as associated with higher lung cancer likelihood.
The paper proposes nurses add questions about hot pot, seafood, instant noodles, grilled foods, secondhand smoke, incense, and cooking during lung cancer assessments.
Key findings
01The logistic regression model reported abnormal blood cadmium as 300.15 times more likely and abnormal urine cadmium as 17.79 times more likely for lung cancer.
02The survey reported hot pot by 78.9%, seafood by 73.4%, and instant noodles by 70.3%, and the paper linked these preferences to cadmium measures.
03The paper recommends adding questions about cooking frequency, incense burning, and diet type to admission nursing assessment.
STILL TO COME
How it was doneWhat they foundWhat it means for RNs
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What it does not show
The model was built from a company-administered biological database, and the paper does not report funding or conflicts beyond authorized access. The database analysis used 689 samples from patients aged 5 to 90 years, and the paper does not describe a separate comparison group of people without lung cancer. The clinical validation included only 128 patients with lung adenocarcinoma, recruited by convenience sampling from specialized cancer hospitals, and 91.4% lived in northern Taiwan, so it cannot show how the model performs in other patients or settings. The paper reports different model performance values in different sections, including logistic regression AUC 0.720 in the database comparison and AUC 0.893 in clinical validation. The nursing assessment suggestions are proposals from the authors; the study did not test whether adding these questions improves patient care or outcomes.
Declared interests
No explicit funding or conflict-of-interest statement is included. The paper states that access to the biological database was authorized by FUGA Biotechnology Co., Ltd., which administered the database.
The easy way to misread this
Do not conclude that avoiding these foods or exposures will lower lung cancer risk or that cadmium causes lung cancer. The study reports associations and model performance, not a tested intervention, and the validation sample had only lung adenocarcinoma patients without a comparison group.