RNOtherRevista latino-americana de enfermagem2025

Analysis of the influence of the COVID-19 pandemic on maternal mortality trends, 2011-2021.

Mariana Vitor Peppe, Fernanda Bruzadelli Paulino da Costa, Livia Sanches Pedrilio and 3 others

PMID 41191696

WHAT IT FOUND

Maternal deaths in São Paulo rose during the pandemic, reaching 87.02 per 100,000 live births in 2021.

Indirect causes became predominant, while direct obstetric deaths did not rise.

Key findings

01The total maternal mortality ratio in São Paulo reached 87.02 deaths per 100,000 live births in 2021, the highest value in the series.

02Indirect maternal deaths showed a 70.5% annual growth from 2019 to 2021.

03Direct maternal deaths did not show an upward trend from 2017 to 2021; the trend was stationary.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

Because the data are aggregated, the study cannot say which individual women were exposed to which care or why each death occurred. It compares time periods without individual-level exposure data, so it cannot prove that the pandemic caused the trend. Some regional health departments had years with no maternal deaths, so individual regional models were not possible. The findings are from São Paulo, so they may not apply to places with different maternity care systems.

The easy way to misread this

Do not read the rise in maternal deaths as proof that the pandemic alone caused it or that a specific care model could have prevented it. The study uses aggregate records and cannot link individual deaths to individual exposures, treatments or services.

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The study

Participants
3,339 maternal deaths among women aged 10 to 49 years in São Paulo, 2011-2021; aggregate live-birth records were the denominator
Certainty of evidence
Low

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Cite

Mariana Vitor Peppe, Fernanda Bruzadelli Paulino da Costa, Livia Sanches Pedrilio, et al. Analysis of the influence of the COVID-19 pandemic on maternal mortality trends, 2011-2021. Revista latino-americana de enfermagem. 2025.

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