An investigation into closed-loop treatment of neurological disorders based on sensing mitochondrial dysfunction.
Scott D Adams, Abbas Z Kouzani, Susannah J Tye, Kevin E Bennet, Michael Berk
PMID 29439744WHAT IT FOUND
No patient outcomes are reported.
A mitochondrial dysfunction closed-loop treatment model is proposed, but not tested.
What this paper is
This is a narrative review and theoretical engineering model. It summarizes links between mitochondrial dysfunction and neurological disorders and proposes a closed-loop treatment system using sensors, controllers and effectors. This paper did not study patients or measure outcomes, so there is nothing here to change therapy practice.
The easy way to misread this
Do not read the proposed closed-loop model as evidence that mitochondrial sensing treatment works. This paper did not study patients or measure outcomes.