Adverse-Event Free Survival, Hospitalizations, and Mortality in Left Ventricular Assist Device Recipients: A Rural-Urban Cohort Comparison.
Windy Alonso, Judith E Hupcey, Lisa Kitko and 2 others
PMID 31365445WHAT IT FOUND
Rural and urban LVAD patients did not differ in time to first adverse event.
Rural patients had shorter time to first hospitalization, but adding distance from the center changed that result. Urban patients had a greater reported mortality risk.
Key findings
01The primary outcome was event-free survival, and rural-urban status did not influence adverse-event free survival time.
02Rural recipients had reduced hospitalization-free survival and a higher reported hazard of unplanned hospitalization, but adding distance from the implanting center made the difference nonsignificant.
03In adjusted models, the paper reported a significantly greater hazard for urban recipients than rural recipients, and age was a significant predictor of survival.
STILL TO COME
How it was doneWhat they foundWhat it means for RNs
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What it does not show
The study used data from one academic medical center in the northeastern United States, so results may not apply to other regions or centers. Rural and urban status was based on the county from the last recorded address at one time, and some recipients may have moved during the study. The registry did not collect geographic location, so addresses were obtained from chart review. Rural and urban groups differed in distance from the implanting center and race, and the analysis did not measure poverty, socioeconomic status, culture, or prior heart failure care. Most recipients were white men, so findings may not apply to more diverse populations. Exclusions removed people who died, were transplanted before discharge, went to hospice, had recent implantations, or lacked county data, which may narrow the sample. The mortality difference was not significant in the unadjusted comparison and appeared only after adjustment.
Declared interests
The authors declared no conflicts of interest.
The easy way to misread this
Do not conclude that rural residence causes more hospitalizations. Rural patients had shorter time to first hospitalization, but when distance from the implanting center was added to the model, the difference became nonsignificant.