OTSLPCohortJournal of intellectual disability research : JIDR2024

Adaptive behaviour deficits in individuals with 3q29 deletion syndrome.

R M Pollak, T L Burrell, J F Cubells and 6 others

PMID 37740553

WHAT IT FOUND

Adaptive behaviour scores were substantially below typical in 32 individuals with 3q29del, especially daily living skills.

Executive function tracked adaptive behaviour more closely than IQ, and more comorbid diagnoses were linked to lower scores.

Key findings

01Adaptive behaviour composite scores averaged 73.91, against a population mean of 100.

02Executive function was more strongly linked to adaptive behaviour than cognitive ability.

03Average adaptive composite scores decreased as the number of comorbid diagnoses increased.

STILL TO COME

How it was doneWhat they foundWhat it means for OTsWhat it means for SLPs

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What it does not show

Small sample size made the analyses exploratory. The wide age range prevented assessment of whether adaptive behaviour is stable across the lifespan. The sample was overwhelmingly white and non-Hispanic, so race and ethnicity effects could not be assessed. Most participants were children and had not passed the age at onset for schizophrenia and related psychotic disorders. Cross-disorder comparisons used published means rather than directly matched controls.

Declared interests

One author reports receiving royalties from Pearson Assessments for the Vineland-3. All other authors report no competing interests.

The easy way to misread this

Do not treat the executive function correlation as proof that executive function training improves adaptive behaviour. This study measured associations in 32 individuals and did not test a treatment.

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