PTOTSLPSystematic ReviewClinical rehabilitation2026

A systematic review of physical activity guidelines for adults with cardio-respiratory diseases: Stepping towards evidence-based recommendations.

Eda Tonga, Thomas Yates, Hannah Worboys and 4 others

PMID 42029388

WHAT IT FOUND

Most cardio-respiratory guidelines encourage physical activity but lack specific instructions on how to prescribe it.

Only 11 of 29 guidelines provided clear details on frequency, intensity, time and type, leaving clinicians to interpret vague advice.

Key findings

01Only 11 of the 29 included guidelines provided specific aerobic physical activity recommendations aligned with FITT principles.

02Strength, endurance, and flexibility exercise recommendations were poorly represented, with only five guidelines providing any guidance.

03Precautions and adaptations were not standardised across guidelines, and guidance on pre-exercise testing or formal medical clearance was limited.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTsWhat it means for SLPs

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What it does not show

The review only included guidelines published in English, potentially missing relevant international guidance. Not all cardio-respiratory diseases were covered, limiting applicability to other conditions. Heterogeneity in how guidelines reported recommendations made it difficult to extract comprehensive FITT data. The review synthesised existing guidance rather than testing patient outcomes, so it cannot confirm whether following these guidelines improves health. It was sometimes unclear if specific instructions applied only to the general population or also to patients with cardio-respiratory disease.

Declared interests

The authors disclosed no potential conflicts of interest. Funding was provided by the European Space Agency, British Heart Foundation, Medical Research Council, and the National Institute for Health and Care Research.

The easy way to misread this

Do not interpret the lack of specific FITT recommendations in most guidelines as evidence that physical activity is unsafe or ineffective for these patients. The review found that guidelines are often vague, not that the underlying evidence for activity is weak. The absence of detailed strength and flexibility guidance reflects a gap in the documents, not a contraindication to these exercises.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →