PTCase SeriesJournal of neuroengineering and rehabilitation2024

A one-year follow-up case series on gait analysis and patient-reported outcomes for persons with unilateral and bilateral transfemoral amputations undergoing direct skeletal fixation.

Diana Toderita, Tiereny McGuire, Alice M Benton and 5 others

PMID 39614354

WHAT IT FOUND

Patient-reported function improved after osseointegration and rehabilitation, but walking speed changed unevenly, with some participants faster and some slower.

This case series cannot show either caused the changes.

Key findings

01Both unilateral and bilateral participants showed improvements across all patient-reported questionnaire scales, with post-operative global score increases of 150% for UTF1, 50% for UTF2, 83% for BTF1, and 100% for BTF2.

02Walking speed increased by 23% for UTF1 but decreased by 15% for UTF2, by 32% for BTF1, and by 6% for BTF2 relative to pre-operative values.

03For the unilateral participants, the second peak of amputated-side hip contact force decreased by 31% for UTF1 and 33% for UTF2, while intact-side hip impulse increased by 19% for UTF1 and 8% for UTF2.

STILL TO COME

How it was doneWhat they foundWhat it means for PTs

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What it does not show

The paper reports only a few individual cases, so the findings cannot be generalised. There was no randomised control group; each participant was compared only with their own earlier data. Osseointegration was given with a standardised rehabilitation programme, so the contribution of surgery alone cannot be separated. Walking speed differed before and after, and walking speed can change joint loading, so some differences may not be due only to osseointegration. Some questionnaire scores were invalid because participants did not answer enough items. The biomechanical model simplified the socket-stump interface and load transfer, and only walking was tested. The study followed participants only to the reported follow-up, and the authors say adaptation may take longer.

Declared interests

The only funding statement supplied names the Office for Veterans' Affairs United Kingdom as funder.

The easy way to misread this

Do not read this as proof that osseointegration alone improves walking or protects joints. The participants also received rehabilitation, walking speed changed between assessments, and the study reports only individual cases without a control group.

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