A high-performance 8 nV/√Hz 8-channel wearable and wireless system for real-time monitoring of bioelectrical signals.
Konstantinos Petkos, Simos Koutsoftidis, Thomas Guiho and 6 others
PMID 31823804WHAT IT FOUND
A small eight-channel wireless recorder measured very weak bioelectrical signals, recorded EEG, EMG, ECG and acceleration, and ran for more than eight hours on a battery.
Tests used two healthy people and a non-human primate.
Key findings
01The device measured input-referred noise of 8 nV/√Hz in the passband and integrated noise of 169 nV rms over 0.5 to 500 Hz.
02In two healthy subjects, the paper reports normalized root mean square errors between wired and wireless recordings of 1.7% for EEG, 1.1% for EMG and 0.39% for ECG.
03The system provided a passband between 0.5 and 500 Hz, achieved 60 dB gain, and ran for more than eight hours on a battery.
STILL TO COME
How it was doneWhat they found
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What it does not show
This is a device engineering paper, not a clinical trial or diagnostic accuracy study. The human recordings came from two healthy subjects, so the paper does not show how the device performs in patients with neurological disorders. The in vivo neural recording came from an anesthetised non-human primate, not from a patient. Several comparisons used previously recorded signals replayed through a waveform generator, not live patient data. The paper does not report whether the device changed diagnosis or therapy.
Declared interests
The funding declaration names Medtronic and the Engineering and Physical Sciences Research Council. The supplied text does not state whether these funders designed, analysed or wrote the study.
The easy way to misread this
Do not read this as evidence that the device improves diagnosis or treatment. It was tested in two healthy people, a non-human primate, and replayed signal segments, not in a clinical study of patients with neurological disease.